Getting an exact number on that is probably next to impossible and there are way too many variables for such a broad subject.
Just in English or in every language? Every Disney franchise or just ducks and mice? Do you count Star Wars and Marvel into this since they are technically owned by Disney? If you answer the last two questions with no, would DuckTales still count? Comics made for merchandise or digital comics on online based platforms that don't use pages in the traditional sense?
Even if we got everyone on this forum to agree on a definitive guideline for this there are still two big things to consider. 1. There would inevitably be a large number of obscure stuff that never got catalogued on inducks or anywhere else online that's going to be overlooked. 2. As Disney comics are still being made and released everywhere in the world, the number is still constantly growing every week or month. Even if someone crazy enough came up with a final number, it's going to be outdated shortly after unless someone managed to stay on top of what's going on across the planet and constantly updated it.